Tumefactive multiple sclerosis – a diagnostic and therapeutic challenge

Weronika Galus1, Katarzyna Zawiślak-Fornagiel1, Ewa Krzystanek2

Affiliation and address for correspondence
Aktualn Neurol 2022, 22 (3), p. 141–145
DOI: 10.15557/AN.2022.0017

Tumefactive multiple sclerosis with the presence of tumefactive demyelinating lesions (TDL) is an infrequent manifestation of multiple sclerosis. It poses a diagnostic challenge, especially in attempts to differentiate it from a central nervous system neoplasm or other demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD). The article reports a case of a 40-year-old female during chronic steroid therapy administered due to an episode of idiopathic transverse myelitis. The patient developed tumour-like brain lesions in the left hemispheric parietal-occipital region. The diagnostic process was hindered by extended steroid treatment and a lack of patient compliance. This case is an example of insufficient knowledge about rare forms of multiple sclerosis and the need for a holistic approach involving a through analysis of medical history and previous medical records.

demyelinating disease of central nervous system, multiple sclerosis, tumefactive multiple sclerosis

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